adverse reaction to omalizumab in patients with chronic urticaria: flare up or ineffectiveness?
نویسندگان
چکیده
omalizumab is a recombinant humanized anti-ig e monoclonal antibody used as the third line treatment of chronic spontaneous urticaria (csu). we report four patients with severe antihistamine-resistant csu, who developed angioedema, anaphylaxis and/or flare up of urticaria at different times following omalizumab therapy.
منابع مشابه
Effects of Omalizumab Treatment in Patients With Refractory Chronic Urticaria
PURPOSE Chronic urticaria (CU) is a common and debilitating disease, and the need for effective treatment has increased. Omalizumab may be an alternative regimen in patients with CU who do not respond to conventional treatments. The aim of this study is to investigate the efficacy and to observe the clinical results of omlizumab in patients with refractory CU. METHODS We conducted a retrospec...
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Chronic idiopathic urticaria (CIU) is a common autoimmune skin condition characterized by spontaneously recurring hives for 6 weeks or longer. The new terminology used for CIU in most countries including Canada is chronic spontaneous urticaria (CSU). CSU is associated with significant psychosocial morbidity with a markedly negative impact on overall quality of life. Conventional approaches with...
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متن کاملOmalizumab for the treatment of chronic idiopathic or spontaneous urticaria.
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عنوان ژورنال:
iranian journal of allergy, asthma and immunologyجلد ۱۵، شماره ۱، صفحات ۸۲-۸۶
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